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Covid Vaccine Reduces the Risk of Clots after Covid Infection!

How could the vaccine have this effect to protect against clots?
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Transcript

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Important to carefully observe the science, reflecting on the strengths and weaknesses of all approaches. That is the scientific method.

This study was started in January 2021 until early 2022. Understanding the timeline is critical for realising this is a historical view of the pandemic during the delta wave. No surprise that some unvaccinated individuals had moderate to severe COVID-19 with associated thromboembolic disease.

In contrast, the Omicron phase would have been overall protective to most of the unvaccinated cohort, except if they had interferon autoantibodies.

COVID-19 vaccination reduced the risk of heart failure, venous thromboembolism and arterial thrombosis/thromboembolism in the acute (30 days) and post-acute (31 to 365 days) phase following SARS-CoV-2 infection. This effect was stronger in the acute phase.
Mercadé-Besora N, Li X, Kolde R, et al The role of COVID-19 vaccines in preventing post-COVID-19 thromboembolic and cardiovascular complications, Heart Published Online First: 12 March 2024. doi: 10.1136/heartjnl-2023-323483

Study outcome design. Study outcomes of interest are defined as a COVID-19 infection followed by one of the complications in the figure, within a year after infection. Outcomes were ascertained in four different time windows after SARS-CoV-2 infection: 0–30 days (namely the acute phase), 31–90 days, 91–180 days and 181–365 days (these last three comprise the post-acute phase).

Number of records (and risk per 10 000 individuals) for acute and post-acute COVID-19 cardiac and thromboembolic complications, across cohorts and databases for any COVID-19 vaccination

(A) Main analysis, (B) Follow-up ends at first vaccine dose after index date
Heartjnl 2023 323483 Inline Supplementary Material 1
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