Speaking with Dr Shankara Chetty about his journey around Covid. Saving the lives of all his patients in semirural South Africa has triggered a potential suspension of his medical license!
"Those who are silent when others are oppressed are guilty of oppression themselves" - Imam Hussain A.S
A Pathophysiological Perspective on COVID-19's Lethal Complication: From Viremia to Hypersensitivity Pneumonitis-like Immune Dysregulation
IL-6 strongly predicts severe SARS-CoV-2 cases and is a major target for blocking downstream macrophage activation syndrome [25]. IL-4 and IL-13 signaling among mast cell activity recruits eosinophils from the bone marrow into the lung through IL-5, a cytokine required for clearance of virus and detected in severe SARS-CoV-2 patients [26,27,28]. Mast cells were 1000-fold higher in BAL of HP patients, and analysis of excessive amounts of histamine in the fluid suggested that the lavage procedure may promote mast cell degranulation [29]. In this vein, eosinopenia in severe SARS-CoV-2 cases and may suggest migration to the lungs
Sanchez-Gonzalez, Marcos A., et al. "A pathophysiological perspective on COVID-19's lethal complication: from viremia to hypersensitivity pneumonitis-like immune dysregulation." Infection & chemotherapy 52.3 (2020): 335.
Timecodes
0:05: ⚕️ Interviews with experts reveal insights on viral autoimmune disease, caution with treatments, and innovative practices in South Africa.
6:09: ⚠️ Controversial statements on pandemic response and interventions leading to persecution.
11:53: ⚕️ Exploring the importance of differential diagnosis in treating patients during the early stages of the pandemic.
17:06: ⚕️ Identification of severe allergic reaction on the 8th day led to successful treatment with steroids and antihistamines.
22:49: 💡 Importance of valuing all observations in scientific discourse despite conflicting narratives.
27:51: ⚕️ Identification of lung pathology and differentiation between pneumonitis and pneumonia based on clinical presentation.
33:21: ⚕️ Histamine release triggers inflammatory progression in Covid-19 patients leading to severe complications.
38:56: ⚕️ Different waves of clinical responses to Covid-19 suggest varying immune reactions and recovery speeds.
44:44: ⚕️ Discussion on successful treatment of Covid patients using a unique approach.
Recap by Tammy AI
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