Has anyone measured IgG4 in people who are say, 12 months to 2 years past their last vaccine to see if their IgG4 antibody levels have indeed fallen? Has anyone discussed this in the literature as yet do you know? Thank you, Dr. M! I always learn from you.
Here is a quote from the blurb about a video from the Merogenomics youtube channel "The good news is shared in that it appears that IgG4 antibody levels start dropping after 6 months post the booster (3rd mRNA injection). This study also confirms the prior observation that memory B cells responsible for the production of IgG4 antibodies also start appearing approximately 6 months after the 2nd shot." ( https://youtu.be/R1lXzpHqM1Y?si=ao4a8JVUf2a_e0e8 )
I'm not certain whether this is actually good news as claimed, but it appears to measure the drop in IgG4 over time.
You would have to measure Ig4-Abs against S-protein. I don‘t know, if a „usual“ lab does this examination. Usually the whole amount of IgG4 is measured - not specifically those against spike. You would have to measure both and set it in ratio.
I'm glad to see a video discussing this issue, because my intuition has been wondering if the ideal strategy for those who are getting all the recommended boosters might be to stay the course. It's a very important question to answer, because these people tend to be higher risk.
I'm not clear why the continuing circulation of JN.1 and other Omicron variants wouldn't stimulate more IgG4 production, obviating the need for more jabs. Would data from people who are constantly exposed to the same allergens, for example some cat owners, be applicable to viral exposure?
How would we measure innate and adaptive immune system exhaustion?
I appreciate all your efforts Dr Mc Millan. I practice functional medicine and focus on brain- gut- immune and covid. I learn so much from you and your excellent work. I just went to the FLCCC educational conference. I would love to see you as a speaker!!
Exactly what I‘ve been thinking about for months! If the vaccinated folks keep in check the viral spread occuring every time they get reinfected because of their IgG4 levels: what if this check system fails by declining? Strange illnesses we are seeing in our hospital.
Hello Dr. McMillan:
I wonder if you have read this paper:
"Assessment of Myocardial 18F-FDG Uptake at PET/CT in Asymptomatic SARS-CoV-2–vaccinated and Nonvaccinated Patients"
https://pubs.rsna.org/doi/10.1148/radiol.230743
Created a whole course on this paper.
Trying to understand the pathophysiology.
https://vejonhealth.learnworlds.com/abnormal-vaccinated-heart
Scary thought, "IgG4 (tolerant antibody) Falls"
Who has the authority to halt vaccinations?
It is the medical professionals, in conjunction with the recipient, who must refuse, regardless of the consequences.
Thank you Dr. McMillan for bringing awareness.
Appreciated.
Has anyone measured IgG4 in people who are say, 12 months to 2 years past their last vaccine to see if their IgG4 antibody levels have indeed fallen? Has anyone discussed this in the literature as yet do you know? Thank you, Dr. M! I always learn from you.
Here is a quote from the blurb about a video from the Merogenomics youtube channel "The good news is shared in that it appears that IgG4 antibody levels start dropping after 6 months post the booster (3rd mRNA injection). This study also confirms the prior observation that memory B cells responsible for the production of IgG4 antibodies also start appearing approximately 6 months after the 2nd shot." ( https://youtu.be/R1lXzpHqM1Y?si=ao4a8JVUf2a_e0e8 )
I'm not certain whether this is actually good news as claimed, but it appears to measure the drop in IgG4 over time.
The paper he is discussing is here: https://www.biorxiv.org/content/10.1101/2023.09.15.557929v2.full
Thanks, Bob.
You would have to measure Ig4-Abs against S-protein. I don‘t know, if a „usual“ lab does this examination. Usually the whole amount of IgG4 is measured - not specifically those against spike. You would have to measure both and set it in ratio.
I'm glad to see a video discussing this issue, because my intuition has been wondering if the ideal strategy for those who are getting all the recommended boosters might be to stay the course. It's a very important question to answer, because these people tend to be higher risk.
Once on the treadmill, it may not be easy to get off.
I'm not clear why the continuing circulation of JN.1 and other Omicron variants wouldn't stimulate more IgG4 production, obviating the need for more jabs. Would data from people who are constantly exposed to the same allergens, for example some cat owners, be applicable to viral exposure?
How would we measure innate and adaptive immune system exhaustion?
I appreciate all your efforts Dr Mc Millan. I practice functional medicine and focus on brain- gut- immune and covid. I learn so much from you and your excellent work. I just went to the FLCCC educational conference. I would love to see you as a speaker!!
Exactly what I‘ve been thinking about for months! If the vaccinated folks keep in check the viral spread occuring every time they get reinfected because of their IgG4 levels: what if this check system fails by declining? Strange illnesses we are seeing in our hospital.
Whoever created the virus did expect this to happen. It's called human genocide
Thank you for your answer.
Will you present your findings?