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Mark A Chlapowski's avatar

Thank you. Question if I may: How does the super hybrid acquired immune tumult (SHAIT) disrupt / down regulate the activity of the innate immune system? Does any such interference at the innate immune level have anything to do with ADE, or is ADE almost all related to SHAIT’s effects at the acquired immune system level? Thank you

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Sounds Like Nonsense's avatar

Pathogenic priming, known as Antibody Mediated Enhanced Disease or Antibody Dependent Enhancement (ADE)

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a body can produce antibody that when it later encounters the real germ, actually enhances disease.

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ADE occurs when the antibodies generated during an immune response recognise and bind to a pathogen, but they are unable to prevent infection. Instead, these antibodies act as ‘Trojan horse,’ allowing the pathogen to get into cells and exacerbate the immune response

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The autoimmune phenomenon would make the body’s own immune cells attack and kill other cells and tissues and organs. Thus patients would likely be a lot sicker with higher complications and death rates. More immunosuppressants would be required, leading to more secondary bacterial and fungal infections. Indeed, this clinical scenario is routinely seen in extremely sick and critical COVID patients.

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