Causes and implications of recurring infections in the vaccinated

Why is there an increased risk of infection in the vaccinated and what are the key implications?

Reviewing the recent pre-print from Cleveland Clinic, USA comparing the infection rates in the vaccine up-to-date versus not up-to date.

Why would Covid infections be higher in the up-to-date vaccinated cohort? In this context, up-to-date means that a person has had all of the boosters that are available to them.

Simon-Makuch hazard plot comparing the cumulative incidence of COVID-19 in the “up-to-date” and “not up-to-date” states with respect to COVID-19 vaccination. Day zero was 29 January 2023, the day the XBB lineages of the Omicron variant became the dominant strains in Ohio. Point estimates and 95% confidence intervals are jittered along the x-axis to improve visibility.

Shrestha, Nabin K., et al. "Risk of Coronavirus Disease 2019 (COVID-19) among Those Up-to-Date and Not Up-to-Date on COVID-19 Vaccination." medRxiv (2023): 2023-06.

I analyse the science and use my clinical understanding to try to predict the possible outcomes at a population level. This webinar will be available for free only on the date of the event, and will subsequently be incorporated into a course.

Causes and Implications of Recurring Infections in the Vaccinated

June 29th, 2023 at 19:00PM UK time

FREE EVENT!

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Agenda: Causes and implications of recurring infections in the vaccinated

Section 1: Latest Research on Increased Risk of Infection in the Vaccinated

• Introduction to the topic: Exploring potential risks associated with Covid vaccines

• Review of recent research paper(s) highlighting increased risk of infection in vaccinated individuals

Section 2: Likely Causes of Recurring Infection

• Understanding the role of IgG4 antibodies in vaccine-related infection

• Exploring the impact of poor interferon response post-vaccination

• Investigating the presence of interferon autoantibodies and their association with recurring infections

Section 3: Likely Disease Presentations in the Short and Medium Term

• Discussion on potential disease manifestations following vaccination

• Analysing short-term and medium-term health outcomes in vaccinated individuals

• Exploring the emerging patterns and trends in vaccinated population

Join Us to Learn More!

• Participants should join in and actively engage in the discussion

• Get a summary of key takeaways from the sessions

• Delve further into the subject matter and participate in a truly interactive learning experience

Note: This event aims to provide an in-depth understanding of the latest research findings regarding increased infection risks among the vaccinated population. It also explores the potential causes of recurring infections, such as IgG4 antibodies, poor interferon response, and interferon autoantibodies. Additionally, participants will gain insights into likely disease presentations in the short and medium term. Join us for an informative and engaging learning experience!

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