Dr. Rennebohm is a pediatrician and pediatric rheumatologist. He is currently largely retired. In 2018 he officially retired from the pediatric rheumatology department at Cleveland Clinic, where he was also the Director of the International Susac Syndrome Consultation Service. Prior to that, he was at Alberta Children’s Hospital in Calgary, Canada, where he was Clinical Professor of Pediatrics and Pediatric Rheumatology; before that he was at Nationwide Children’s Hospital and Ohio State University in Columbus, Ohio, where he was Associate Professor of Pediatrics and Chief of Pediatric Rheumatology for 20 years; and before that he was a pediatric rheumatologist at Cincinnati Children’s Hospital.
He went to medical school at the University of California San Diego (UCSD), at La Jolla, where he graduated with an MD degree in 1972. He has practiced pediatrics for almost 50 years and has been a pediatric rheumatologist for about 42 years.
Although he is no longer in clinical practice or affiliated with a medical school or health care institution, he has continued his intense interests in pediatric rheumatology, Susac syndrome, and now COVID. In fact, throughout the past 2 years he has spent many hours per day on most days of most weeks intensively studying and writing about COVID---because he has realized how profoundly important and complex the COVID situation is.
Want to hear what Geert Vanden Bossche said about this open letter?
Very interesting. Thank you for the interview. Dr Robert Rennebohm, and Dr Philip McMillan will have to make another interview in the future because there are many, still unresolved questions regarding auto-immunity in pediatric patients with Covid-19. There are growing interest around a world about multisystem inflammatory syndrome in children several days to weeks after resolution of the initial infection. One hypothesis is superantigenic characteristics of SARS-CoV-2 with regard to S protein binding to TCRs and hyperactivating T cell responses. The second hypothesis is zonulin-dependent loss of gut mucosal barrier that increases in gut permeability allowing SARS-CoV-2 antigens, including the superantigen-like motif of the spike protein, to traffic across mucosal barriers and into the bloodstream and cause massive inflammation and autoimmune responses. And this has been observed in children only.
Looking forward to see your joint efforts.
So awesome 👏 appreciate your courage 💪